MIT engineers have designed a microfluidic platform that connects engineered tissue from up to 10 organs, allowing them to replicate human-organ interactions. Image: Felice Frankel

MIT engineers develop technology that eliminates testing drugs on humans

A new technology development by MIT engineers now makes it possible for researchers to detect side effects on drugs, without testing them on humans.

Using a microfluidic platform that connects engineered tissues from up to 10 organs, the researchers can precisely replicate human organ interactions for weeks at a time, allowing them to determine the effects the drugs have on different parts of the body.

An example of the benefits of the discovery is that the new technology can detect if a new medicine will treat one organ but have adverse side effects on another.

These chips could also be used to evaluate antibody drugs and other immunotherapies, which are difficult to test thoroughly in animals because they are designed to interact with the human immune system.

For more information about the microfluidic platform, visit the MIT News website here.


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