Collier commissioners consider guesthouse rentals in Urban EstatesLCSO needs help locating man wanted for animal cruelty
Collier commissioners consider guesthouse rentals in Urban Estates Collier commissioners moved forward with a plan to allow urban estates homeowners to rent guesthouses to address a critical shortage of workforce housing.
LCSO needs help locating man wanted for animal cruelty The Lee County Sheriff’s office is looking for a man who is wanted for violating the conditions of his release from jail after he was arrested for animal cruelty.
LOS ANGELES (AP) Matthew Perry’s death under investigation over ketamine level found in actor’s blood An investigation has been opened into the death of Matthew Perry and how the “Friends” actor received the anesthetic ketamine, which was ruled a contributing factor in his death.
FORT MYERS What you need to know about the Caloosahatchee Bridge closure The Florida Department of Transportation has made the decision to close the Caloosahatchee Bridge for 10 weeks while crews work on the bridge. Here’s what you need to know.
Lee County allocates $41.6M in federal money for affordable housing The money comes from the federal government’s Department of Housing and Urban Development. Lee County commissioners voted 5-0 in allocating the money, part of a $1.1 billion Community Development Block Grant-Disaster Recovery fund.Â
Poached closing longtime restaurant in North Naples Poached soon is going to be toast—as in defunct. The local breakfast-lunch restaurant is permanently closing next week in Galleria Shoppes at Vanderbilt in North Naples. Â
PINE ISLAND ‘We’re Pine Island proud,’ Pine Island artists paint power poles Relaunching 20 years later, Pine Island artists have been painting power poles up and down Stringfellow Road to bring back color and vibrancy after Hurricane Ian.
Naples Airport presented with 4 site options in eastern Collier County Environmental Science Associates conducted an exploratory study and met with landowners interested in selling land. ESA whittled that to a list of four sites for a general airport.
Expert: Buying or renting depends on your situation Shelton Weeks, Lucas professor of real estate and director of the Lucas Institute for Real Estate Development and Finance, is asked a lot by students whether they should rent or buy.Â
Attorneys offer update on Bonita Estero Rail Trail project The proposed project hit a milestone in February when the Trust for Public Land secured a purchase and sale agreement for $82 million with the Seminole Gulf Railway on a 14.9-mile segment stretching from Alico Road to Collier County for conversion to a hiking and biking trail.Â
NAPLES Woman arrested for stealing over $150K from Naples Ballet The Naples Police Department arrested a woman for allegedly stealing over $150,000 from the Naples Ballet, a non-profit organization.
NORTH FORT MYERS Duo accused of stealing from North Fort Myers store Southwest Florida Crime Stoppers is seeking information on two people accused of stealing from a North Fort Myers store.
WINK NEWS Lee Commissioners award over $41.6M for rehabilitation of affordable housing units The Lee Board of County Commissioners voted to award more than $41.6 million in Community Development Block Grants-Disaster Recovery funds.
New York (AP) Defense rests without Trump testifying in hush money case The defense rests its case without ex-President Donald Trump taking the witness stand in his New York hush money case. Closing arguments are expected next Tuesday.
IMMOKALEE Immokalee girls robotics team competes at VEX Worlds The Immokalee High School girls robotics team got to compete and learn at the VEX Robotics World Championships in Dallas.
Collier commissioners consider guesthouse rentals in Urban Estates Collier commissioners moved forward with a plan to allow urban estates homeowners to rent guesthouses to address a critical shortage of workforce housing.
LCSO needs help locating man wanted for animal cruelty The Lee County Sheriff’s office is looking for a man who is wanted for violating the conditions of his release from jail after he was arrested for animal cruelty.
LOS ANGELES (AP) Matthew Perry’s death under investigation over ketamine level found in actor’s blood An investigation has been opened into the death of Matthew Perry and how the “Friends” actor received the anesthetic ketamine, which was ruled a contributing factor in his death.
FORT MYERS What you need to know about the Caloosahatchee Bridge closure The Florida Department of Transportation has made the decision to close the Caloosahatchee Bridge for 10 weeks while crews work on the bridge. Here’s what you need to know.
Lee County allocates $41.6M in federal money for affordable housing The money comes from the federal government’s Department of Housing and Urban Development. Lee County commissioners voted 5-0 in allocating the money, part of a $1.1 billion Community Development Block Grant-Disaster Recovery fund.Â
Poached closing longtime restaurant in North Naples Poached soon is going to be toast—as in defunct. The local breakfast-lunch restaurant is permanently closing next week in Galleria Shoppes at Vanderbilt in North Naples. Â
PINE ISLAND ‘We’re Pine Island proud,’ Pine Island artists paint power poles Relaunching 20 years later, Pine Island artists have been painting power poles up and down Stringfellow Road to bring back color and vibrancy after Hurricane Ian.
Naples Airport presented with 4 site options in eastern Collier County Environmental Science Associates conducted an exploratory study and met with landowners interested in selling land. ESA whittled that to a list of four sites for a general airport.
Expert: Buying or renting depends on your situation Shelton Weeks, Lucas professor of real estate and director of the Lucas Institute for Real Estate Development and Finance, is asked a lot by students whether they should rent or buy.Â
Attorneys offer update on Bonita Estero Rail Trail project The proposed project hit a milestone in February when the Trust for Public Land secured a purchase and sale agreement for $82 million with the Seminole Gulf Railway on a 14.9-mile segment stretching from Alico Road to Collier County for conversion to a hiking and biking trail.Â
NAPLES Woman arrested for stealing over $150K from Naples Ballet The Naples Police Department arrested a woman for allegedly stealing over $150,000 from the Naples Ballet, a non-profit organization.
NORTH FORT MYERS Duo accused of stealing from North Fort Myers store Southwest Florida Crime Stoppers is seeking information on two people accused of stealing from a North Fort Myers store.
WINK NEWS Lee Commissioners award over $41.6M for rehabilitation of affordable housing units The Lee Board of County Commissioners voted to award more than $41.6 million in Community Development Block Grants-Disaster Recovery funds.
New York (AP) Defense rests without Trump testifying in hush money case The defense rests its case without ex-President Donald Trump taking the witness stand in his New York hush money case. Closing arguments are expected next Tuesday.
IMMOKALEE Immokalee girls robotics team competes at VEX Worlds The Immokalee High School girls robotics team got to compete and learn at the VEX Robotics World Championships in Dallas.
MGN NEW YORK (AP) At Jef Boeke’s lab, you can whiff an odor that seems out of place, as if they were baking bread here. But he and his colleagues are cooking up something else altogether: yeast that works with chunks of man-made DNA. Scientists have long been able to make specific changes in the DNA code. Now, they’re taking the more radical step of starting over, and building redesigned life forms from scratch. Boeke, a researcher at New York University, directs an international team of 11 labs on four continents working to “rewrite” the yeast genome, following a detailed plan they published in March. Their work is part of a bold and controversial pursuit aimed at creating custom-made DNA codes to be inserted into living cells to change how they function, or even provide a treatment for diseases. It could also someday help give scientists the profound and unsettling ability to create entirely new organisms. The genome is the entire genetic code of a living thing. Learning how to make one from scratch, Boeke said, means “you really can construct something that’s completely new.” The research may reveal basic, hidden rules that govern the structure and functioning of genomes. But it also opens the door to life with new and useful characteristics, like microbes or mammal cells that are better than current ones at pumping out medications in pharmaceutical factories, or new vaccines. The right modifications might make yeast efficiently produce new biofuels, Boeke says. Some scientists look further into the future and see things like trees that purify water supplies and plants that detect explosives at airports and shopping malls. Also on the horizon is redesigning human DNA. That’s not to make genetically altered people, scientists stress. Instead, the synthetic DNA would be put into cells, to make them better at pumping out pharmaceutical proteins, for example, or perhaps to engineer stem cells as a safer source of lab-grown tissue and organs for transplanting into patients. Some have found the idea of remaking human DNA disconcerting, and scientists plan to get guidance from ethicists and the public before they try it. Still, redesigning DNA is alarming to some. Laurie Zoloth of Northwestern University, a bioethicist who’s been following the effort, is concerned about making organisms with “properties we cannot fully know.” And the work would disturb people who believe creating life from scratch would give humans unwarranted power, she said. “It is not only a science project,” Zoloth said in an email. “It is an ethical and moral and theological proposal of significant proportions.” Rewritten DNA has already been put to work in viruses and bacteria. Australian scientists recently announced that they’d built the genome of the Zika virus in a lab, for example, to better understand it and get clues for new treatments. At Harvard University, Jeffrey Way and Pamela Silver are working toward developing a harmless strain of salmonella to use as a vaccine against food poisoning from salmonella and E. coli, as well as the diarrhea-causing disease called shigella. A key goal is to prevent the strain from turning harmful as a result of picking up DNA from other bacteria. That requires changing its genome in 30,000 places. “The only practical way to do that,” Way says, “is to synthesize it from scratch.” The cutting edge for redesigning a genome, though, is yeast. Its genome is bigger and more complex than the viral and bacterial codes altered so far. But it’s well-understood and yeast will readily swap man-made DNA for its own. Still, rewriting the yeast genome is a huge job. It’s like a chain with 12 million chemical links, known by the letters, A, C, G and T. That’s less than one-hundredth the size of the human genome, which has 3.2 billion links. But it’s still such a big job that Boeke’s lab and scientists in the United States, Australia, China, Singapore, and the United Kingdom are splitting up the work. By the time the new yeast genome is completed, researchers will have added, deleted or altered about a million DNA letters. Boeke compares a genome to a book with many chapters, and researchers are coming out with a new edition, with chapters that allow the book to do something it couldn’t do before. To redesign a particular stretch of yeast DNA, scientists begin with its sequence of code letters – nature’s own recipe. They load that sequence into a computer, then tell the computer to make specific kinds of changes. For example one change might let them rearrange the order of genes, which might reveal strategies to make yeast grow better, says NYU researcher Leslie Mitchell. Once the changes are made, the new sequence used as a blueprint. It is sent to a company that builds chunks of DNA containing the new sequence. Then these short chunks are joined together in the lab to build ever longer strands. The project has so far reported building about one-third of the yeast genome. Boeke hopes the rest of the construction will be done by the end of the year. But he says it will take longer to test the new DNA and fix problems, and to finally combine the various chunks into a complete synthetic genome. Last year, Boeke and others announced a separate effort, what is now called Genome Project-write or GP-write . It is chiefly focused on cutting the cost of building and testing large genomes, including human ones, by more than 1,000-fold within 10 years. The project is still seeking funding. In the meantime, leaders of GP-write have started discussions of ethical, legal and social issues. And they realize the idea of making a human genome is a sensitive one. “The notion that we could actually write a human genome is simultaneously thrilling to some and not so thrilling to others,” Boeke said. “So we recognize this is going to take a lot of discussion.”