Published: Aug 04, 2012 3:19 AM EDT
Updated: Aug 05, 2012 6:31 AM EDT

OAKLAND, Calif. (AP) - The Oakland Athletics won in 15 innings for the second time this week, with Jemile Weeks hitting a leadoff triple and scoring on Coco Crisp's sacrifice fly to beat Toronto 5-4 Friday night.

Weeks was a star Monday night, too, when his sacrifice fly in the bottom of the 15th beat Tampa Bay.

The A's became the first team to play a pair of 15-inning games in a five-day span since the Los Angeles Dodgers in 2006. This win took 4 hours, 47 minutes; the victory over the Rays lasted more than 5 hours.

Toronto lost its sixth in a row. Jeff Mathis hit a tying, three-run homer in the ninth for the Blue Jays, and Omar Vizquel was thrown out at the plate in the 12th.

Blue Jays manager John Farrell used a five-man infield and also shifted his lineup. After the designated hitter spot was lost, Aaron Loup (1-1) became the first Toronto pitcher to bat in an AL game.

Travis Blackley (4-3) pitched three innings for the win.

The A's posted their 13th walk-off victory of the season. Oakland has won 10 straight one-run games, its longest such streak since 2000.

A's closer Ryan Cook retired the first two batters in the ninth. But David Cooper and Rajai Davis each singled and Mathis hit his sixth home run, making it 4-all.

Mathis' homer spoiled Dan Straily's major league debut.

Straily averaged 11.39 strikeouts per nine innings in the minors this year, the best rate in pro ball. Called up from Triple-A before the game, he allowed one run and five hits in six innings, striking out five.

Jonny Gomes and Chris Carter each homered for the A's. Brandon Inge and Josh Reddick also drove in runs as Oakland improved to 21-6 since the start of July.

Crisp and Yoenis Cespedes, who left the game with a right wrist sprain, each had two hits.

Toronto starter Brett Cecil allowed four runs on nine hits over five innings. Brad Lincoln went 3 1-3 scoreless innings for the Blue Jays, giving up one hit.

NOTES: The 2006 Dodgers lost in 15 innings at Arizona on Aug. 25, then beat Cincinnati in 16 innings on Aug. 29, STATS LLC said. ... Inge has a 13-game hitting streak. ... Toronto INF Brett Lawrie left the game after one inning with tightness in his rib cage. ... A's OF RHP Ricky Romero (8-8, 5.69) goes for the Blue Jays on Saturday. He never finished the second inning in his last outing against the A's and has lost seven straight. He's 4-1 against the A's in seven career starts. The A's will start A.J. Griffin (3-0, 2.51).